Biden Hints at Executive Order on Gun Control

Vice President Biden, meeting today with outside groups on gun safety, told reporters he has already started putting together a list of recommendations that he plans to issue next Tuesday.

He has suggested the administration would be ready to take executive action on the issue, which would not require votes from Congress. That prospect has raised alarm bells for gun rights advocates.

Biden told reporters Thursday, during a meeting a with sportsmen, women and wildlife groups, that he would deliver the list of recommendations to the president on Jan. 15, and that an improved system for background checks has emerged as a a priority for the stakeholders he's met so far. Guns have been at the top of the White House agenda since the December shootings at Sandy Hook Elementary School in Newtown, Conn.

"I am putting together a series of recommendations for the president that will, that he will take a look at. There's a real, very tight window to do this," Biden said at the top of his meeting with advocates for sportsmen, sportswomen and wildlife interest groups. "I committed to him I'd have these recommendations to him by Tuesday. And it doesn't mean it's the end of the discussion, but the public wants us to act."

Biden said he has not reached any conclusions just yet but recounted the recommendations that have been made to him from the various stakeholders he's met with over the past month. The vice president emphasized the consensus emerging from the meetings on the need to strengthen the background check system.

"So far, a surprising recurrence of suggestions that we have universal background checks, not just close the gun show loophole, but total, universal background checks, even including private sales," Biden said.

Other suggestions offered at the meetings have centered on gun safety and the responsibility that goes along with gun ownership, dealing with high capacity magazines, and the ability of federal agencies to do research on gun violence.

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Biden sat down with representatives of the NRA and other supporters of gun rights on the second day of this week's meetings on gun violence.

He said at one meeting that he has "never quite heard so much talk about high-capacity magazines" as he has since the shootings in Newtown.

Biden met with gun-violence victims' groups and proponents of gun control on Wednesday. Thursday was his opportunity to get a different side of the story. Biden met with the National Rifle Association and Attorney General Eric Holder met with representatives from Wal-Mart, one of the largest sellers of firearms in the country.

"There are executive orders, executive action that can be taken. We haven't decided what that is yet, but we're compiling it all with the help the attorney general and all the rest of the cabinet members, as well as legislative action, we believe, is required," Biden said.

Spokesmen for the NRA and Wal-Mart confirmed representatives from their organizations would be included in the meetings Thursday. The NRA said it would be represented by James J. Baker, its top lobbyist. Advocates for sportsmen, women's groups, wildlife groups and gun owners were also invited. The vice president is slated to meet with members of the entertainment industry in the evening.

In December, the NRA called for armed officers to be placed in every school after the massacre at Sandy Hook Elementary.

Wal-Mart initially turned down an invitation to participate in the talks but reversed its decision after it "underestimated the expectation to attend the meeting on Thursday in person," a spokesman said.

"We take this issue very seriously and are committed staying engaged in this discussion as the administration and Congress work toward a consensus on the right path forward," David Tovar, vice president of corporate communications for Wal-Mart, said.

The latest meetings come one day after Biden held a first round of talks this week with gun safety advocacy groups and victims of gun violence. Speaking to reporters before the meeting, the vice president expressed the administration's commitment to develop effective gun policy by considering all ideas.

Colin Goddard, a survivor of the shooting at Virginia Tech University in 2007, participated in the meeting at the White House Wednesday and said the talks gave the groups "encouragement from the highest office in the country."

"I was really encouraged by seeing how focused and determined the administration is in seeing comprehensive changes to the gun violence in America," Goddard, who is now the assistant director for federal legislation at the Brady Campaign to Prevent Gun Violence, told ABC News. "It was really great to see even the Vice President of the United States of America supporting us. He wants to see this done to the end and bringing us all to the table to share our personal stories, share our ideas about what our proposals could be."

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String of bombings kill 101, injure 200 in Pakistan

QUETTA, Pakistan (Reuters) - At least 101 people were killed in bombings in two Pakistani cities on Thursday in one of the country's bloodiest days in recent years, officials said, with most casualties caused by sectarian attacks in Quetta.

The bombings underscored the myriad threats Pakistani security forces face from homegrown Sunni extremist groups, the Taliban insurgency in the northwest and the less well-known Baloch insurgency in the southwest.

On Thursday evening, two coordinated explosions killed at least 69 people and injured more than 100 in Quetta, the provincial capital of Balochistan, said Deputy Inspector of Police Hamid Shakil.

The first attack, in a crowded snooker hall, was a suicide bombing, local residents said. About ten minutes later, a car bomb exploded, they said. Five policemen and a cameraman were among the dead from that blast.

The attacks happened in a predominately Shia neighborhood and banned sectarian group Lashkar-e-Jhangvi claimed responsibility. The extremist Sunni group targets Shias, who make up about 20 percent of Pakistani's population.

Targeted killings and bombings of Shia communities are common in Pakistan, and rights groups say hundreds of Shia were killed last year. Militant groups in Balochistan frequently bomb or shoot Shia passengers on buses travelling to neighboring Iran.

The killers are rarely caught and some Shia activists say militants work alongside elements of Pakistan's security forces, who see them as a potential bulwark against neighboring India.

Many Pakistanis fear their nation could become the site of a regional power struggle between Saudi Arabia, source of funding for Sunni extremist groups, and Iran, which is largely Shia.

But sectarian tensions are not the only source of violence.

The United Baloch Army claimed responsibility for a blast in Quetta's market earlier in the day. It killed 11 people and injured more than 40, mostly vegetable sellers and secondhand clothes dealers, police officer Zubair Mehmood said. A child was also killed.

The group is one of several fighting for independence for Balochistan, an arid, impoverished region with substantial gas, copper and gold reserves, which constitutes just under half of Pakistan's territory and is home to about 8 million of the country's population of 180 million.

SWAT BOMBING

In another incident Thursday, 21 were killed and more than 60 injured in a bombing when people gathered to hear a religious leader speak in Mingora, the largest city in the northwestern province of Swat, police and officials at the Saidu Sharif hospital said.

"The death toll may rise as some of the injured are in critical condition and we are receiving more and more injured people," said Dr. Niaz Mohammad.

It has been more than two years since a militant attack has claimed that many lives in Swat.

The mountainous region, formerly a tourist destination, has been administered by the Pakistani army since their 2009 offensive drove out Taliban militants who had taken control.

But Talibans retain the ability to attack in Swat and shot schoolgirl campaigner Malala Yousufzai in Mingora last October.

A Taliban spokesman said they were not responsible for Thursday's bombing.

(Additional reporting by Jibran Ahmad in Peshawar, Pakistan; Writing by Katharine Houreld; Editing by Mark Heinrich and Jason Webb)

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US will stand by Afghanistan, Panetta tells Karzai

WASHINGTON: The United States sought to assure Afghan President Hamid Karzai on Thursday that it would remain committed to his country even as US officials weigh a major withdrawal of American forces.

After an elaborate military ceremony for Karzai outside the Pentagon, US Defense Secretary Leon Panetta told his "distinguished visitor" that more than 10 years of war had paved the way for Afghanistan to stand on its own.

"After a long and difficult past, we finally are, I believe, at the last chapter of establishing a sovereign Afghanistan that can govern and secure itself for the future," Panetta said.

"We've come a long way towards a shared goal of establishing a nation that you and we can be proud of, one that never again becomes a safe haven for terrorism."

He also offered Karzai assurances that the future of the two countries was now entwined.

"We have sacrificed together -- that has created a bond that will not be broken in the future," Panetta said.

Since US-led troops toppled the Taliban in 2001 after the September 11 attacks, the Afghan president has had a stormy relationship with his US allies, and officials here want to demonstrate Washington's full-fledged support.

The talks come as President Barack Obama, newly elected to a second term, charts a plan to pull most of the 66,000 US troops out of Afghanistan -- well down from a high of about 100,000.

The United States and its NATO allies have already agreed to withdraw combat troops by the end of 2014, but questions remain on a US training and security role after that.

Throughout his visit, Karzai is expected to push for a substantial US military presence in Afghanistan after 2014.

But some White House officials favour only a light footprint of several thousand troops, and Ben Rhodes, a deputy national security adviser, even suggested Tuesday the United States might pull out all of its troops.

US military officers privately acknowledged those comments about a total withdrawal were primarily designed as a tactic in negotiations with Kabul.

Karzai was also due to meet later Thursday with US Secretary of State Hillary Clinton, for talks and an official dinner at the State Department, before a White House summit on Friday with Obama.

Among the issues topping the agenda at the State Department are progress on reconciliation talks with the Taliban, as well as the distribution of US aid to Afghanistan.

"We have had some modest steps forward in recent months, including a commitment by Pakistan to support Afghan reconciliation," State Department spokeswoman Victoria Nuland said.

Karzai has also pressed for more US assistance to go directly into Afghan coffers, instead of being distributed via non-governmental and aid organizations.

"We've made a pledge that about 50 per cent ought to go through the Afghan government," Nuland said earlier this week. But she stressed that this was "tied to our expectation that the Afghan government will in turn meet the commitments... with regard to continuing to make progress on corruption, on transparency, on accountability."

For his part, Karzai thanked Panetta for the US military's contributions and for the red-carpet ceremony, saying he was hopeful Washington and Kabul would work out an agreement allowing a future US military role beyond 2014.

"Afghanistan will, with the help that you provide, be able to provide security to its people and to protect its borders; so Afghanistan would not ever again be threatened by terrorists from across our borders," he said.

Karzai also voiced confidence the two countries can "work out a modality for a bilateral security agreement that will ensure the interests of Afghanistan and also the interests of the United States."

- AFP/jc

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Prayers for Akbaruddin Owaisi in temple

HYDERABAD: About 50 Hindus living in the Old City performed a 'havan' at a temple for the release of Majlis-e-Ittehadul Muslimeen (MIM) leader Akbaruddin Owaisi, who was arrested on Sunday over a hate speech.

The 41-year-old Majlis leader was remanded to 14-day judicial custody this week with multiple cases being filed against him. Legal experts say chances of his immediate release are remote.

But while the speech incurred the wrath of people across the country, a section of residents living in and around Jagjivanram Nagar, mostly Hindus, are fond of Akbaruddin for the development work he had carried out in the past as a legislator.

The Chandrayangutta MLA has found supporters among some Hindus of the Old City with 'puja' organiser Kanduri Anita saying that many people from the neighbourhood had gathered for the 'havan' and 'aarti' in the evening, which took a few by surprise.

"Akbaruddin Owaisi got small sheds constructed for this Maisamma temple and Boolakshmi temple, both of which are in Jagjivanram Nagar. He also got borewell pumps repaired. All of us have prayed for his release," said Anita.

Further, scores of MIM leader's supporters gathered at Dargah Yousufain in Nampally to express solidarity with the arrested legislator and offered prayers for his release.

While shops in the Old City were open and the RTC resumed services after its fleet stayed off the roads on Wednesday, people in street corners were seen discussing the issue with many enquiring when their leader will be released.

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Flu season hits early and, in some places, hard

NEW YORK (AP) — From the Rocky Mountains to New England, hospitals are swamped with people with flu symptoms. Some medical centers have limited visitors, and one Pennsylvania hospital set up a tent outside its ER to handle the feverish patients.

Flu season in the U.S. has hit early and, in some places, hard. But whether this will be considered a bad season by the time it has run its course in the spring remains to be seen.

"Those of us with gray hair have seen worse," said Dr. William Schaffner, a flu expert at Vanderbilt University in Nashville.

The evidence so far is pointing to a moderate season, Schaffner and others believe. It just looks bad compared with last year — an unusually mild one.

Flu usually doesn't blanket the country until late January or February, but it is already widespread in more than 40 states.

What's probably complicating the situation: The main influenza virus this year tends to make people sicker. And there are other bugs out there causing flu-like illnesses. So what people are calling the flu may, in fact, be something else.

"There may be more of an overlap than we normally see," said Dr. Joseph Bresee, who tracks the flu for the Centers for Disease Control and Prevention.

The flu's early arrival in the U.S. coincided with spikes in a variety of other viruses, including a childhood malady that mimics flu and a new norovirus that causes what some people call "stomach flu."

Most people don't undergo lab tests to confirm flu, and the symptoms are so similar that it's sometimes hard to distinguish flu from other viruses, or even a cold. Over the holidays, 250 people were sickened at a Mormon missionary training center in Utah, but the culprit turned out to be a norovirus, not the flu.

Flu is a major contributor, though, to what's going on.

"I'd say 75 percent," said Dr. Dan Surdam, head of the emergency department at Cheyenne Regional Medical Center, Wyoming's largest hospital. The 17-bed ER saw its busiest day ever last week, with 166 visitors.

The early onslaught has resulted in a spike in hospitalizations, prompting hospitals to take steps to deal with the influx and protect other patients from getting sick, including restricting visits from children, requiring family members to wear masks, and banning anyone with flu symptoms from maternity wards.

One hospital in Allentown, Pa., this week set up a tent for a steady stream of patients with flu symptoms.

But so far, "what we're seeing is a typical flu season," said Terry Burger, director of infection control and prevention for the hospital, Lehigh Valley Hospital-Cedar Crest.

On Wednesday, Boston declared a public health emergency, and all the flu activity has caused some to question whether this year's flu shot is working.

There's a new flu vaccine each year, based on the best guess of what flu viruses will be strongest that year. This year's vaccine is well-matched to what's going around. The government estimates that between a third and a half of Americans have gotten the vaccine.

But the vaccine isn't foolproof, and even those who were vaccinated can still get sick. At best, the vaccine may be only 75 percent effective in younger people and even less so in the elderly and people with weak immune systems.

Health officials are analyzing the vaccine's effectiveness, but early indications are that about 60 percent of all vaccinated people have been protected from the flu. That's in line with how effective flu vaccines have been in other years.

In New York City, 57-year-old Judith Quinones suffered her worst case of flu-like illness in years, laid up for nearly a month with fever and body aches. "I just couldn't function," she said.

She decided to skip getting a flu shot last fall. But her daughter got the shot. "And she got sick twice," Quinones said.

On average, about 24,000 Americans die each flu season, according to the CDC.

Flu usually peaks in midwinter. Symptoms can include fever, cough, runny nose, head and body aches and fatigue. Some people also suffer vomiting and diarrhea, and some develop pneumonia or other severe complications.

Most people with flu have a mild illness and can help themselves and protect others by staying home and resting. But people with severe symptoms should see a doctor. They may be given antiviral drugs or other medications to ease symptoms.

The last bad flu season involved a swine flu that hit in two waves in the spring and fall of 2009. But that was considered a unique strain, different from the regular winter flu.

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Online:

CDC flu: http://www.cdc.gov/flu/index.htm

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Holmes Took Disturbing Photos Before Massacre

Hours before James Holmes allegedly carried out a massacre at a Colorado movie theater he took a series of menacing self-portraits with his dyed orange hair curling out of from under a black skull cap and his eyes covered with black contacts.

A prosecutor told the court after the photographs were shown that Holmes had a "depravity of human heart."

Those haunting photographs, found on his iPhone, were shown in court today on the last day of a preliminary testimony that will lead to a decision on whether the case will go to trial. The hearing concluded without Holmes' defense calling any witnesses.

The judge's decision on whether the case will proceed to trial is expected on Friday.

Holmes, 25, is accused of opening fire on a crowded movie theater in Aurora, Colo., on July 20, 2012, killing 12 people and wounding 58 others during a showing of "Dark Knight Rises."

The photos presented in court showed Holmes mugging for his iPhone camera just hours before the shooting.

Click here for full coverage of the Aurora movie theater shooting.

Half-a-dozen photos showed Holmes with his clownish red-orange hair curled out from underneath a black skull cap. He wore black contact lenses in some of the pictures.

In one particularly disturbing image, he was making a scowling face with his tongue out. He was whistling in another photo. Holmes is smiling in his black contacts and flaming hair in yet another with the muzzle of one of his Glock pistols in the forefront.

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Yet another showed him dressed in black tactical gear, posing with an AR-15 rifle.

Victims' families in the courtroom stared straight ahead, showing little emotion while the photos were shown. Tom Teves, whose son Alex was killed in the theater, kept an intense stare on the pictures.

Other photos seized from the iPhone show pictures that a detective testified were taken of the interior of the Aurora movie theater in the days leading up to the attack, on June 29, July 5 and July 11.

Before the prosecution called for the photos, public defender Tammy Brady objected. Prosecutor Karen Pearson said that the photos showed deliberation and extreme indifference. Judge William Sylvester overruled the objection and the photos were released.

In Pearson's closing statement, she said there is an abundance of direct evidence that Holmes "wanted to kill call of them. He knew what he was doing."

She said that Holmes had a "depravity of human heart" and that he "went into the theater without knowing or caring who they are." The prosecutor said he "picked the perfect venue for the perfect crime."

Pearson said prosecutors made a decision not to include all of the people who were in theaters eight and nine that night. If they had, they could have had 1,500 counts against Holmes. Instead, they included anyone who had physical injuries, including those with gunshot wounds and those who were hurt running out of the theater. There are 166 counts in all.

The judge has taken the case under advisement and there will be a status hearing or arraignment on Friday when the judge will decide whether the case will proceed to a full trial. Holmes' attorneys have not yet said whether they plan on using a insanity defense, in which case Holmes could possibly be deemed unfit to stand trial. Another possibility is that the hearing could set the stage for a plea deal.

This week's testimony has included emotional testimony from first responders, details about Holmes' elaborately booby trapped apartment, a rundown of his arsenal of legally purchased weapons and descriptions of his bizarre behavior following the shooting.

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Venezuela court endorses Chavez inauguration delay

CARACAS (Reuters) - Venezuela's top court endorsed the postponement of Hugo Chavez's inauguration this week and ruled on Wednesday that the cancer-stricken president and his deputy would continue in their roles, despite a cacophony of opposition complaints.

Critics had argued the 58-year-old's absence from his own swearing-in ceremony on January 10 meant a caretaker president must be appointed. Chavez has not been seen in public nor heard from in almost a month following surgery in Cuba.

"Right now we cannot say when, how or where the president will be sworn in," Supreme Court Chief Judge Luisa Morales told a news conference.

"As president re-elect there is no interruption of performance of duties ... The inauguration can be carried out at a later date before the Supreme Court."

The decision opens the door in theory for Chavez to remain in office for weeks or months more from a Cuban hospital bed - though there is no evidence he is even conscious.

It leaves the South American country in the hands of Vice President Nicolas Maduro, as de facto leader of the government.

The opposition say that is a brazen violation of the constitution, and that Maduro should leave office on Thursday when the current presidential term had been due to expire.

They say National Assembly boss Diosdado Cabello, another powerful Chavez ally, should take over the running of the country while new elections would be organized within 30 days.

Maduro would be the ruling Socialist Party's candidate.

Government leaders insist Chavez, 58, is fulfilling his duties as head of state, even though official medical bulletins say he suffered complications after the surgery, including a severe lung infection, and has had trouble breathing.

His resignation or death would transform politics in the OPEC nation, where he is revered by poor supporters thankful for his social largesse, but denounced by opponents as a dictator.

RALLY PLANNED FOR THURSDAY

Moody's Investors Service warned on Wednesday that Venezuela's sovereign credit rating, already at junk status, faces short-term risks over any political transition.

Prices of Venezuela's widely traded bonds have soared lately on Chavez's health woes, but dipped this week as investors' expectations of a quick government change apparently dimmed.

The president has undergone four operations, as well as weeks of chemotherapy and radiation treatment, since being diagnosed with an undisclosed type of cancer in his pelvic area in June 2011.

He looked to have staged a remarkable recovery from the illness last year, winning a new six-year term at a hard-fought election in October. But within weeks of his victory he had to return to Havana for more treatment.

The government has called for a huge rally outside the Miraflores presidential palace in Caracas on Thursday, and allied leaders including Uruguay's Jose Mujica and Bolivia's Evo Morales have said they will visit - despite Chavez's absence.

Argentine President Cristina Fernandez, a close friend, has announced plans to visit Chavez in Cuba on Friday.

The unprecedented silence by Chavez, who is well known for his hours-long rambling speeches, has convinced many Venezuelans that his 14 years in power may be coming to an end.

Unlike after his previous operations in Cuba, no photographs have been published of him recuperating, and social media in Venezuela is buzzing with rumors he is on life support.

Cabello, the pugnacious head of the National Assembly, has repeatedly ruled out taking over as caretaker president to order a new presidential election, saying Chavez remains in charge.

"Tomorrow we will all go to the Miraflores palace," he told a televised Socialist Party meeting on Wednesday. "The people will be invested as president. We are all Chavez!"

(Additional reporting by Marianna Parraga and Diego Ore; Editing by Andrew Cawthorne)

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Oil prices weaken after US energy report

NEW YORK: Crude oil prices retreated Wednesday after a US oil inventory report pointed to large increases in refined petroleum products.

Oil prices for US benchmark West Texas Intermediate settled five cents lower at US$93.10 a barrel.

In London, the Brent contract for February finished at US$111.76 a barrel, losing 18 cents from Tuesday.

The decline came after a weekly report by the US Energy Information Administration reported surprisingly large increases in stocks of gasoline and distillate fuel, a category that includes home heating oil.

Gasoline stockpiles in the week ending January 4 surged by 7.4 million barrels, far higher than forecasts for a rise of 2.1 million barrels. Reserves of distillates soared 6.8 million barrels, well beyond the expected 1.4-million-barrel increase.

And US crude oil stocks grew by 1.3 million barrels, below the 2.2 million-barrel forecast according to a survey by Dow Jones Newswires.

Crude futures also fell Wednesday on lingering concerns over the US economy despite solid earnings from aluminium giant Alcoa, analysts said.

Global markets have shifted their attention from the US fiscal debate to corporate earnings to gauge the health of the world's biggest economy and largest oil consuming nation going into 2013.

"The recent fiscal cliff-inspired rally is fast becoming the 'Ghost of Christmas Past' as traders shift their focus to US corporate earnings," said Jason Hughes, head of premium client management at IG Markets in Singapore.

"Solid gains notched up in the first week of the year across global markets are so far just being nibbled at by fears of disappointing fourth-quarter profits across US blue chip stocks."

- AFP/jc

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Maharashtra plans water trains for drought areas

MUMBAI: With the state witnessing an acute drought, the state government has decided to adopt unprecedented measures.

Anticipating that certain parts of Marathwada will go completely dry by March, the state government has drawn up a plan to transport water for drinking in railway wagons. At the state cabinet meeting on Wednesday, chief minister Prithviraj Chavan informed colleagues that initial discussions in this regard had been held with officials from Western Railway and Central Railway. Chavan further informed that the railway officials have agreed to provide three rakes for the purpose. He further said that the arrangement could provide means to transport five lakh litres of water to the drought-prone areas daily.

The total water storage in reservoirs in the Marathwada belt is barely 18%. Big dams like Ujni and Jayakwadi have almost gone dry.

Pressing the contingency plan, the state cabinet decided to provide a contingency grant of Rs 2 crore to collectors in drought-hit districts for emergency operations.

CM Prithviraj Chavan said the schemes have now been reserved for drinking water. The state has issued instructions asking authorities to prioritize completion of incomplete water supply schemes in drought-hit areas. Chavan has also issued directives asking officials to ensure that alternative means of employment are made available in the affected areas. The kharif crop production has been hit.

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Retooling Pap test to spot more kinds of cancer

WASHINGTON (AP) — For years, doctors have lamented that there's no Pap test for deadly ovarian cancer. Wednesday, scientists reported a tantalizing hint that one day, there might be.

Researchers are trying to retool the Pap, a test for cervical cancer that millions of women get, so that it could spot early signs of other gynecologic cancers, too.

How? It turns out that cells can flake off of tumors in the ovaries or the lining of the uterus, and float down to rest in the cervix, where Pap tests are performed. These cells are too rare to recognize under the microscope. But researchers from Johns Hopkins University used some sophisticated DNA testing on the Pap samples to uncover the evidence — gene mutations that show cancer is present.

In a pilot study, they analyzed Pap smears from 46 women who already were diagnosed with either ovarian or endometrial cancer. The new technique found all the endometrial cancers and 41 percent of the ovarian tumors, the team reported Wednesday in the journal Science Translational Medicine.

This is very early-stage research, and women shouldn't expect any change in their routine Paps. It will take years of additional testing to prove if the so-called PapGene technique really could work as a screening tool, used to spot cancer in women who thought they were healthy.

"Now the hard work begins," said Hopkins oncologist Dr. Luis Diaz, whose team is collecting hundreds of additional Pap samples for more study and is exploring ways to enhance the detection of ovarian cancer.

But if it ultimately pans out, "the neat part about this is, the patient won't feel anything different," and the Pap wouldn't be performed differently, Diaz added. The extra work would come in a lab.

The gene-based technique marks a new approach toward cancer screening, and specialists are watching closely.

"This is very encouraging, and it shows great potential," said American Cancer Society genetics expert Michael Melner.

"We are a long way from being able to see any impact on our patients," cautioned Dr. Shannon Westin of the University of Texas MD Anderson Cancer Center. She reviewed the research in an accompanying editorial, and said the ovarian cancer detection would need improvement if the test is to work.

But she noted that ovarian cancer has poor survival rates because it's rarely caught early. "If this screening test could identify ovarian cancer at an early stage, there would be a profound impact on patient outcomes and mortality," Westin said.

More than 22,000 U.S. women are diagnosed with ovarian cancer each year, and more than 15,000 die. Symptoms such as pain and bloating seldom are obvious until the cancer is more advanced, and numerous attempts at screening tests have failed.

Endometrial cancer affects about 47,000 women a year, and kills about 8,000. There is no screening test for it either, but most women are diagnosed early because of postmenopausal bleeding.

The Hopkins research piggybacks on one of the most successful cancer screening tools, the Pap, and a newer technology used along with it. With a standard Pap, a little brush scrapes off cells from the cervix, which are stored in a vial to examine for signs of cervical cancer. Today, many women's Paps undergo an additional DNA-based test to see if they harbor the HPV virus, which can spur cervical cancer.

So the Hopkins team, funded largely by cancer advocacy groups, decided to look for DNA evidence of other gynecologic tumors. It developed a method to rapidly screen the Pap samples for those mutations using standard genetics equipment that Diaz said wouldn't add much to the cost of a Pap-plus-HPV test. He said the technique could detect both early-stage and more advanced tumors. Importantly, tests of Paps from 14 healthy women turned up no false alarms.

The endometrial cancers may have been easier to find because cells from those tumors don't have as far to travel as ovarian cancer cells, Diaz said. Researchers will study whether inserting the Pap brush deeper, testing during different times of the menstrual cycle, or other factors might improve detection of ovarian cancer.

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